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Best South America Cruises

Showing 176-200 of 826 results
7-night south america cruise
Balcony From
$5,538
AmaWaterways – AmaMelodia
Departs Feb 16, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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12-night south america cruise
Suite From
$11,175
Silversea – Silver Ray
5.03 Reviews
Departs Feb 17, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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14-night south america cruise
Inside From
$2,539
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Feb 21, 2028 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,489
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Feb 26, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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19-night south america cruise
Suite From
$10,200
Silversea – Silver Shadow
4.540 Reviews
Departs Feb 27, 2028 from Rio de Janeiro, Brazil
Up to 2 deals
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11-night south america cruise
Suite From
$13,090
Silversea – Silver Cloud
4.316 Reviews
Departs Feb 29, 2028 from Puerto Williams, Chile
Up to 3 deals including an Avoya Exclusive
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20-night south america cruise
Suite From
$17,510
Silversea – Silver Ray
5.03 Reviews
Departs Feb 29, 2028 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,679
AmaWaterways – AmaMelodia
Departs Mar 01, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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15-night south america cruise
Inside From
$2,899
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Mar 06, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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32-night south america cruise
Inside From
$5,784
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Mar 06, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,639
AmaWaterways – AmaMelodia
Departs Mar 15, 2028 from Barranquilla, Colombia
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17-night south america cruise
Inside From
$3,149
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Mar 21, 2028 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,479
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Apr 08, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,379
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Apr 22, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,029
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs May 06, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,139
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs May 13, 2028 from Barranquilla, Colombia
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7-night south america cruise
Balcony From
$4,239
AmaWaterways – AmaMelodia
Departs Aug 09, 2028 from Cartagena, Colombia
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7-night south america cruise
Balcony From
$4,029
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Aug 26, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,129
AmaWaterways – AmaMelodia
Departs Sep 13, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,379
AmaWaterways – AmaMelodia
Departs Oct 04, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,379
AmaWaterways – AmaMelodia
Departs Oct 25, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,479
AmaWaterways – AmaMelodia
Departs Nov 01, 2028 from Cartagena, Colombia
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14-night south america cruise
Inside From
$7,099
50% Off List
Oceania Cruises – Aurelia
Departs Nov 08, 2028 from Bridgetown, Barbados
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,939
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Nov 11, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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20-night south america cruise + tour
Inside From
$6,875
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 16, 2028 from Rio de Janeiro, Brazil
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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