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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,948

50% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 18, 2026

Ports:

Departs Dec 18, 2026 from Fort de France, Martinique

Up to 3 deals

Inside From

$2,948

50% Off List

List Price

$5,929

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$696

67% Off List

MSC Cruises – MSC World America

Date:

Dec 19, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Dec 19, 2026 from Miami, Florida

Up to 2 deals

Inside From

$696

67% Off List

List Price

$2,130

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$941

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Dec 19, 2026 View Other Dates →

Ports:

Departs Dec 19, 2026 from Fort de France, Martinique

Up to 2 deals

Inside From

$941

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,331

55% Off List

MSC Cruises – MSC World America

Date:

Dec 19, 2026 View Other Dates →

Ports:

Departs Dec 19, 2026 from Miami, Florida

Up to 2 deals

Inside From

$2,331

55% Off List

List Price

$5,186

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$746

62% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 20, 2026 View Other Dates →

Ports:

Departs Dec 20, 2026 from Port Canaveral, Florida

Up to 1 deal

Inside From

$746

62% Off List

List Price

$1,955

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$810

53% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Dec 20, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Dec 20, 2026 from Galveston, Texas

Up to 1 deal

Inside From

$810

53% Off List

List Price

$1,715

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,342

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Dec 20, 2026 View Other Dates →

Ports:

Departs Dec 20, 2026 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,342

View Expanded Details

MSC Cruises MSC Seaside itinerary map

14-night caribbean cruise

Inside From

$1,942

53% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 21, 2026

Ports:

Departs Dec 21, 2026 from Miami, Florida

Up to 2 deals

Inside From

$1,942

53% Off List

List Price

$4,106

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$1,503

64% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Dec 23, 2026 View Other Dates →

Ports:

Miami → Ocho Rios → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Dec 23, 2026 from Miami, Florida

Up to 3 deals

Inside From

$1,503

64% Off List

List Price

$4,169

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$1,000

57% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 26, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Dec 26, 2026 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,000

57% Off List

List Price

$2,320

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,251

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Dec 26, 2026

Ports:

Departs Dec 26, 2026 from Fort de France, Martinique

Up to 2 deals

Inside From

$1,251

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$1,438

53% Off List

MSC Cruises – MSC World America

Date:

Dec 26, 2026 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Dec 26, 2026 from Miami, Florida

Up to 2 deals

Inside From

$1,438

53% Off List

List Price

$3,087

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,185

55% Off List

MSC Cruises – MSC World America

Date:

Dec 26, 2026 View Other Dates →

Ports:

Departs Dec 26, 2026 from Miami, Florida

Up to 2 deals

Inside From

$2,185

55% Off List

List Price

$4,866

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$741

67% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 27, 2026

Ports:

Port Canaveral → Puerto Plata → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Dec 27, 2026 from Port Canaveral, Florida

Up to 1 deal

Inside From

$741

67% Off List

List Price

$2,233

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,692

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Dec 27, 2026

Ports:

Departs Dec 27, 2026 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,692

View Expanded Details

MSC Cruises MSC World Europa itinerary map

14-night caribbean cruise

Inside From

$2,111

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Dec 29, 2026

Ports:

Departs Dec 29, 2026 from Bridgetown, Barbados

Up to 2 deals

Inside From

$2,111

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,428

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 31, 2026

Ports:

Departs Dec 31, 2026 from Bridgetown, Barbados

Up to 3 deals

Inside From

$2,428

51% Off List

List Price

$4,932

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,598

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 01, 2027

Ports:

Departs Jan 01, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$1,598

51% Off List

List Price

$3,261

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$369

63% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 02, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Jan 02, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$369

63% Off List

List Price

$1,004

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

8-night caribbean cruise

Inside From

$548

57% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 02, 2027 View Other Dates →

Ports:

Departs Jan 02, 2027 from Miami, Florida

Up to 3 deals

Inside From

$548

57% Off List

List Price

$1,266

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$772

57% Off List

MSC Cruises – MSC World America

Date:

Jan 02, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 02, 2027 from Miami, Florida

Up to 2 deals

Inside From

$772

57% Off List

List Price

$1,810

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$929

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 02, 2027 View Other Dates →

Ports:

Departs Jan 02, 2027 from Fort de France, Martinique

Up to 1 deal

Inside From

$929

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,136

45% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 02, 2027 View Other Dates →

Ports:

Departs Jan 02, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,136

45% Off List

List Price

$2,077

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,365

57% Off List

MSC Cruises – MSC World America

Date:

Jan 02, 2027 View Other Dates →

Ports:

Departs Jan 02, 2027 from Miami, Florida

Up to 2 deals

Inside From

$1,365

57% Off List

List Price

$3,146

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$392

60% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jan 03, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jan 03, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$392

60% Off List

List Price

$975

View Expanded Details

Showing 276-300 of 1,181 results

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