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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$454

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 18, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Jan 18, 2027 from Miami, Florida

Up to 1 deal

Inside From

$454

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Oceanview From

$769

53% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 18, 2027 View Other Dates →

Ports:

Departs Jan 18, 2027 from La Romana, Dominican Republic

Up to 2 deals

Oceanview From

$769

53% Off List

List Price

$1,634

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,330

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 18, 2027

Ports:

Departs Jan 18, 2027 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,330

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$213

62% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 21, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jan 21, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$213

62% Off List

List Price

$563

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$342

67% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 23, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Jan 23, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$342

67% Off List

List Price

$1,044

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$949

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 23, 2027 View Other Dates →

Ports:

Departs Jan 23, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$949

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

6-night caribbean cruise

Inside From

$280

71% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 24, 2027

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Miami

Departs Jan 24, 2027 from Miami, Florida

Up to 4 deals

Inside From

$280

71% Off List

List Price

$954

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$327

66% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jan 24, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jan 24, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$327

66% Off List

List Price

$975

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,136

45% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 24, 2027

Ports:

Departs Jan 24, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,136

45% Off List

List Price

$2,077

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Balcony From

$1,882

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 24, 2027 View Other Dates →

Ports:

Departs Jan 24, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Balcony From

$1,882

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$224

58% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 25, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 25, 2027 from Miami, Florida

Up to 3 deals

Inside From

$224

58% Off List

List Price

$527

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$659

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 25, 2027 View Other Dates →

Ports:

Departs Jan 25, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$659

51% Off List

List Price

$1,333

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,320

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 25, 2027

Ports:

Departs Jan 25, 2027 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,320

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$219

61% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 28, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jan 28, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$219

61% Off List

List Price

$563

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,608

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 28, 2027 View Other Dates →

Ports:

Departs Jan 28, 2027 from Bridgetown, Barbados

Up to 2 deals

Inside From

$1,608

48% Off List

List Price

$3,078

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$223

54% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 29, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 29, 2027 from Miami, Florida

Up to 3 deals

Inside From

$223

54% Off List

List Price

$483

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$309

68% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 30, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Jan 30, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$309

68% Off List

List Price

$980

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

8-night caribbean cruise

Inside From

$547

56% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 30, 2027

Ports:

Miami → Nassau → San Juan → Saint Maarten (Phillipsburg) → Charlotte Amalie → Miami

Departs Jan 30, 2027 from Miami, Florida

Up to 4 deals

Inside From

$547

56% Off List

List Price

$1,246

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$782

45% Off List

MSC Cruises – MSC World America

Date:

Jan 30, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 30, 2027 from Miami, Florida

Up to 2 deals

Inside From

$782

45% Off List

List Price

$1,410

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,019

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 30, 2027 View Other Dates →

Ports:

Departs Jan 30, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$1,019

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$233

63% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 31, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jan 31, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$233

63% Off List

List Price

$622

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$303

69% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jan 31, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jan 31, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$303

69% Off List

List Price

$975

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,258

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 31, 2027 View Other Dates →

Ports:

Departs Jan 31, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,258

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$239

59% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Feb 01, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Feb 01, 2027 from Miami, Florida

Up to 3 deals

Inside From

$239

59% Off List

List Price

$587

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,380

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 01, 2027

Ports:

Departs Feb 01, 2027 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,380

View Expanded Details

Showing 326-350 of 1,181 results

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