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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,112

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 03, 2027 View Other Dates →

Ports:

Departs Jan 03, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,112

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$221

61% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 07, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jan 07, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$221

61% Off List

List Price

$563

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$376

64% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 09, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Jan 09, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$376

64% Off List

List Price

$1,044

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$568

58% Off List

MSC Cruises – MSC World America

Date:

Jan 09, 2027 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 09, 2027 from Miami, Florida

Up to 2 deals

Inside From

$568

58% Off List

List Price

$1,367

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$756

63% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 09, 2027 View Other Dates →

Ports:

Departs Jan 09, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$756

63% Off List

List Price

$2,036

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$879

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 09, 2027 View Other Dates →

Ports:

Departs Jan 09, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$879

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

6-night caribbean cruise

Inside From

$350

65% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 10, 2027 View Other Dates →

Ports:

Miami → Grand Turk → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jan 10, 2027 from Miami, Florida

Up to 4 deals

Inside From

$350

65% Off List

List Price

$994

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$359

65% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jan 10, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jan 10, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$359

65% Off List

List Price

$1,015

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,122

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 10, 2027 View Other Dates →

Ports:

Departs Jan 10, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,122

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,176

45% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 10, 2027

Ports:

Departs Jan 10, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,176

45% Off List

List Price

$2,157

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$221

56% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 11, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 11, 2027 from Miami, Florida

Up to 2 deals

Inside From

$221

56% Off List

List Price

$507

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,330

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 11, 2027

Ports:

Departs Jan 11, 2027 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,330

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$226

60% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 14, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jan 14, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$226

60% Off List

List Price

$563

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,548

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 14, 2027

Ports:

Departs Jan 14, 2027 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,548

48% Off List

List Price

$2,958

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Oceanview From

$2,685

42% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Jan 14, 2027

Ports:

Departs Jan 14, 2027 from Miami, Florida

Up to 2 deals

Oceanview From

$2,685

42% Off List

List Price

$4,616

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$286

41% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 15, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 15, 2027 from Miami, Florida

Up to 2 deals

Inside From

$286

41% Off List

List Price

$483

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$343

66% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 16, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Jan 16, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$343

66% Off List

List Price

$1,004

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

8-night caribbean cruise

Inside From

$610

51% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 16, 2027

Ports:

Miami → Saint Maarten (Phillipsburg) → Saint Johns → Charlotte Amalie → Puerto Plata → Miami

Departs Jan 16, 2027 from Miami, Florida

Up to 4 deals

Inside From

$610

51% Off List

List Price

$1,246

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$826

48% Off List

MSC Cruises – MSC World America

Date:

Jan 16, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 16, 2027 from Miami, Florida

Up to 2 deals

Inside From

$826

48% Off List

List Price

$1,590

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$843

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 16, 2027 View Other Dates →

Ports:

Departs Jan 16, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$843

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,136

45% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Jan 16, 2027

Ports:

Departs Jan 16, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,136

45% Off List

List Price

$2,077

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,533

48% Off List

MSC Cruises – MSC World America

Date:

Jan 16, 2027 View Other Dates →

Ports:

Departs Jan 16, 2027 from Miami, Florida

Up to 2 deals

Inside From

$1,533

48% Off List

List Price

$2,926

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$331

70% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jan 17, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jan 17, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$331

70% Off List

List Price

$1,115

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$882

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Jan 17, 2027 View Other Dates →

Ports:

Departs Jan 17, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$882

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$269

49% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 18, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 18, 2027 from Miami, Florida

Up to 2 deals

Inside From

$269

49% Off List

List Price

$527

View Expanded Details

Showing 301-325 of 1,181 results

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