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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$573

56% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Mar 07, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Mar 07, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$573

56% Off List

List Price

$1,295

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,272

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 07, 2027 View Other Dates →

Ports:

Departs Mar 07, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,272

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$1,408

36% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Mar 07, 2027 View Other Dates →

Ports:

Miami → Ocho Rios → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Mar 07, 2027 from Miami, Florida

Up to 2 deals

Inside From

$1,408

36% Off List

List Price

$2,199

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$294

60% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 08, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 08, 2027 from Miami, Florida

Up to 3 deals

Inside From

$294

60% Off List

List Price

$727

View Expanded Details

MSC Cruises MSC World Europa itinerary map

14-night caribbean cruise

Balcony From

$2,728

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 09, 2027

Ports:

Departs Mar 09, 2027 from Bridgetown, Barbados

Up to 2 deals

Balcony From

$2,728

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$264

64% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Mar 11, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Mar 11, 2027 from Port Canaveral, Florida

Up to 1 deal

Inside From

$264

64% Off List

List Price

$743

View Expanded Details

MSC Cruises MSC Opera itinerary map

4-night caribbean cruise

Inside From

$269

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 11, 2027

Ports:

Bridgetown → Fort de France → Saint Johns → Road Town (Tortola) British Virgin Islands → La Romana

Departs Mar 11, 2027 from Bridgetown, Barbados

Inside From

$269

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$258

63% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 12, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 12, 2027 from Miami, Florida

Up to 3 deals

Inside From

$258

63% Off List

List Price

$703

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$416

71% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 13, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Mar 13, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$416

71% Off List

List Price

$1,444

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$780

55% Off List

MSC Cruises – MSC World America

Date:

Mar 13, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 13, 2027 from Miami, Florida

Up to 2 deals

Inside From

$780

55% Off List

List Price

$1,730

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$999

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 13, 2027 View Other Dates →

Ports:

Departs Mar 13, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$999

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,086

63% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 13, 2027 View Other Dates →

Ports:

Departs Mar 13, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,086

63% Off List

List Price

$2,936

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$670

58% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Mar 14, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Mar 14, 2027 from Galveston, Texas

Up to 1 deal

Inside From

$670

58% Off List

List Price

$1,595

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Balcony From

$1,438

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 14, 2027 View Other Dates →

Ports:

Departs Mar 14, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Balcony From

$1,438

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$616

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 15, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Mar 15, 2027 from Miami, Florida

Up to 1 deal

Inside From

$616

View Expanded Details

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Inside From

$768

62% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Mar 18, 2027 View Other Dates →

Ports:

Miami → Curacao → Bonaire → Oranjestad → Cabo Rojo → Ocho Rios → Miami

Departs Mar 18, 2027 from Miami, Florida

Up to 2 deals

Inside From

$768

62% Off List

List Price

$2,046

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$358

54% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 19, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 19, 2027 from Miami, Florida

Up to 3 deals

Inside From

$358

54% Off List

List Price

$783

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$522

65% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 20, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Mar 20, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$522

65% Off List

List Price

$1,504

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$859

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 20, 2027 View Other Dates →

Ports:

Departs Mar 20, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$859

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$916

48% Off List

MSC Cruises – MSC World America

Date:

Mar 20, 2027 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 20, 2027 from Miami, Florida

Up to 2 deals

Inside From

$916

48% Off List

List Price

$1,747

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,139

63% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 20, 2027 View Other Dates →

Ports:

Departs Mar 20, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,139

63% Off List

List Price

$3,076

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$383

74% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Mar 21, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Mar 21, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$383

74% Off List

List Price

$1,455

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,092

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 21, 2027 View Other Dates →

Ports:

Departs Mar 21, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,092

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$792

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 22, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Mar 22, 2027 from Miami, Florida

Up to 1 deal

Inside From

$792

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$339

57% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Mar 25, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Mar 25, 2027 from Port Canaveral, Florida

Up to 1 deal

Inside From

$339

57% Off List

List Price

$783

View Expanded Details

Showing 401-425 of 1,181 results

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