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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$758

56% Off List

MSC Cruises – MSC World America

Date:

Apr 24, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 24, 2027 from Miami, Florida

Up to 3 deals

Inside From

$758

56% Off List

List Price

$1,710

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$297

57% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Apr 25, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Apr 25, 2027 from Port Canaveral, Florida

Up to 1 deal

Inside From

$297

57% Off List

List Price

$684

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$722

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 26, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Apr 26, 2027 from Miami, Florida

Up to 1 deal

Inside From

$722

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,908

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 29, 2027 View Other Dates →

Ports:

Departs Apr 29, 2027 from Bridgetown, Barbados

Up to 3 deals

Inside From

$1,908

49% Off List

List Price

$3,764

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Balcony From

$1,937

44% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Departs Apr 30, 2027 from Fort de France, Martinique

Up to 3 deals

Balcony From

$1,937

44% Off List

List Price

$3,473

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$804

49% Off List

MSC Cruises – MSC World America

Date:

May 01, 2027 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 01, 2027 from Miami, Florida

Up to 3 deals

Inside From

$804

49% Off List

List Price

$1,587

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,681

49% Off List

MSC Cruises – MSC World America

Date:

May 01, 2027 View Other Dates →

Ports:

Departs May 01, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,681

49% Off List

List Price

$3,266

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$483

69% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

May 02, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs May 02, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$483

69% Off List

List Price

$1,535

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$306

54% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 03, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 03, 2027 from Miami, Florida

Up to 3 deals

Inside From

$306

54% Off List

List Price

$669

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$949

47% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 07, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs May 07, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$949

47% Off List

List Price

$1,801

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$738

57% Off List

MSC Cruises – MSC World America

Date:

May 08, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 08, 2027 from Miami, Florida

Up to 3 deals

Inside From

$738

57% Off List

List Price

$1,710

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$517

66% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

May 09, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs May 09, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$517

66% Off List

List Price

$1,535

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$379

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 14, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 14, 2027 from Miami, Florida

Up to 3 deals

Inside From

$379

43% Off List

List Price

$665

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$367

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 17, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 17, 2027 from Miami, Florida

Up to 3 deals

Inside From

$367

45% Off List

List Price

$669

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$438

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

May 20, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs May 20, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$438

48% Off List

List Price

$843

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$407

42% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 21, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 21, 2027 from Miami, Florida

Up to 3 deals

Inside From

$407

42% Off List

List Price

$705

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$967

45% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 21, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs May 21, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$967

45% Off List

List Price

$1,767

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$706

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 24, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs May 24, 2027 from Miami, Florida

Up to 1 deal

Inside From

$706

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$438

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

May 27, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs May 27, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$438

48% Off List

List Price

$843

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$479

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 28, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 28, 2027 from Miami, Florida

Up to 3 deals

Inside From

$479

43% Off List

List Price

$845

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$502

46% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

May 30, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs May 30, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$502

46% Off List

List Price

$922

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$427

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 31, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs May 31, 2027 from Miami, Florida

Up to 3 deals

Inside From

$427

46% Off List

List Price

$789

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$746

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 31, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs May 31, 2027 from Miami, Florida

Up to 1 deal

Inside From

$746

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,381

46% Off List

MSC Cruises – MSC World America

Date:

Jun 05, 2027 View Other Dates →

Ports:

Departs Jun 05, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,381

46% Off List

List Price

$4,446

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$413

52% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jun 06, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jun 06, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$413

52% Off List

List Price

$862

View Expanded Details

Showing 451-475 of 1,181 results

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