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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$412

51% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 26, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 26, 2027 from Miami, Florida

Up to 3 deals

Inside From

$412

51% Off List

List Price

$843

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$488

69% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 27, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Mar 27, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$488

69% Off List

List Price

$1,584

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

8-night caribbean cruise

Inside From

$745

73% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Mar 27, 2027 View Other Dates →

Ports:

Departs Mar 27, 2027 from Miami, Florida

Up to 3 deals

Inside From

$745

73% Off List

List Price

$2,806

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$799

58% Off List

MSC Cruises – MSC World America

Date:

Mar 27, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 27, 2027 from Miami, Florida

Up to 2 deals

Inside From

$799

58% Off List

List Price

$1,890

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,049

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 27, 2027 View Other Dates →

Ports:

Departs Mar 27, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$1,049

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,426

46% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Mar 27, 2027 View Other Dates →

Ports:

Departs Mar 27, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,426

46% Off List

List Price

$2,657

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$1,578

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Mar 28, 2027 View Other Dates →

Ports:

Departs Mar 28, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Inside From

$1,578

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$384

59% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 29, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 29, 2027 from Miami, Florida

Up to 3 deals

Inside From

$384

59% Off List

List Price

$947

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$702

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 29, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Mar 29, 2027 from Miami, Florida

Up to 1 deal

Inside From

$702

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$724

59% Off List

MSC Cruises – MSC World America

Date:

Apr 03, 2027 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 03, 2027 from Miami, Florida

Up to 3 deals

Inside From

$724

59% Off List

List Price

$1,767

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Inside From

$982

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Apr 03, 2027 View Other Dates →

Ports:

Departs Apr 03, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$982

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,010

58% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 03, 2027 View Other Dates →

Ports:

Departs Apr 03, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,010

58% Off List

List Price

$2,396

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,451

57% Off List

MSC Cruises – MSC World America

Date:

Apr 03, 2027 View Other Dates →

Ports:

Departs Apr 03, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,451

57% Off List

List Price

$3,406

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

6-night caribbean cruise

Inside From

$395

67% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Apr 04, 2027 View Other Dates →

Ports:

Miami → Grand Turk → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Apr 04, 2027 from Miami, Florida

Up to 3 deals

Inside From

$395

67% Off List

List Price

$1,214

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night caribbean cruise

Suite From

$2,814

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Apr 04, 2027 View Other Dates →

Ports:

Departs Apr 04, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 2 deals

Suite From

$2,814

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$481

59% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 10, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Apr 10, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$481

59% Off List

List Price

$1,184

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$758

55% Off List

MSC Cruises – MSC World America

Date:

Apr 10, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 10, 2027 from Miami, Florida

Up to 3 deals

Inside From

$758

55% Off List

List Price

$1,670

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,481

54% Off List

MSC Cruises – MSC World America

Date:

Apr 10, 2027 View Other Dates →

Ports:

Departs Apr 10, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,481

54% Off List

List Price

$3,226

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$290

59% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Apr 11, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Apr 11, 2027 from Port Canaveral, Florida

Up to 1 deal

Inside From

$290

59% Off List

List Price

$704

View Expanded Details

MSC Cruises MSC Opera itinerary map

3-night caribbean cruise

Inside From

$209

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 12, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Bridgetown

Departs Apr 12, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$209

View Expanded Details

MSC Cruises MSC Opera itinerary map

4-night caribbean cruise

Inside From

$269

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 12, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Apr 12, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$269

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$303

53% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Apr 15, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Apr 15, 2027 from Port Canaveral, Florida

Up to 1 deal

Inside From

$303

53% Off List

List Price

$643

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$466

68% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Apr 18, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Apr 18, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$466

68% Off List

List Price

$1,455

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$712

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 19, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Apr 19, 2027 from Miami, Florida

Up to 1 deal

Inside From

$712

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$559

53% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 24, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Apr 24, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$559

53% Off List

List Price

$1,184

View Expanded Details

Showing 426-450 of 1,181 results

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