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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 20, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jan 20, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$359

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 21, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jan 21, 2028 from Miami, Florida

Up to 3 deals

Inside From

$359

44% Off List

List Price

$643

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$360

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 23, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jan 23, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$360

45% Off List

List Price

$660

View Expanded Details

MSC Cruises MSC Seashore itinerary map

6-night caribbean cruise

Inside From

$549

46% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 23, 2028 View Other Dates →

Ports:

Miami → Puerto Plata → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jan 23, 2028 from Miami, Florida

Up to 3 deals

Inside From

$549

46% Off List

List Price

$1,014

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$1,073

47% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Jan 23, 2028

Ports:

Miami → Montego Bay → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Jan 23, 2028 from Miami, Florida

Up to 3 deals

Inside From

$1,073

47% Off List

List Price

$2,039

View Expanded Details

MSC Cruises MSC Seashore itinerary map

14-night caribbean cruise

Inside From

$1,248

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 23, 2028

Ports:

Departs Jan 23, 2028 from Miami, Florida

Up to 3 deals

Inside From

$1,248

48% Off List

List Price

$2,381

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$366

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 24, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jan 24, 2028 from Miami, Florida

Up to 3 deals

Inside From

$366

43% Off List

List Price

$647

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$615

49% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 24, 2028

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Jan 24, 2028 from Miami, Florida

Up to 1 deal

Inside From

$615

49% Off List

List Price

$1,200

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$819

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 24, 2028 View Other Dates →

Ports:

Departs Jan 24, 2028 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$819

49% Off List

List Price

$1,609

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,570

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 24, 2028 View Other Dates →

Ports:

Departs Jan 24, 2028 from La Romana, Dominican Republic

Inside From

$1,570

49% Off List

List Price

$3,088

View Expanded Details

MSC Cruises MSC World Asia itinerary map

14-night caribbean cruise

Inside From

$3,109

49% Off List

MSC Cruises – MSC World Asia

Date:

Jan 25, 2028

Ports:

Departs Jan 25, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$3,109

49% Off List

List Price

$6,148

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$349

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 28, 2028 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jan 28, 2028 from Miami, Florida

Up to 3 deals

Inside From

$349

44% Off List

List Price

$623

View Expanded Details

MSC Cruises MSC Seashore itinerary map

14-night caribbean cruise

Inside From

$1,258

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Jan 29, 2028

Ports:

Departs Jan 29, 2028 from Miami, Florida

Up to 3 deals

Inside From

$1,258

48% Off List

List Price

$2,401

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$380

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 30, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jan 30, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$380

46% Off List

List Price

$700

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$535

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jan 30, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jan 30, 2028 from Galveston, Texas

Up to 3 deals

Inside From

$535

49% Off List

List Price

$1,055

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$681

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jan 31, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Jan 31, 2028 from Miami, Florida

Up to 1 deal

Inside From

$681

47% Off List

List Price

$1,276

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$819

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jan 31, 2028 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Jan 31, 2028 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$819

49% Off List

List Price

$1,609

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Feb 03, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Feb 03, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Inside From

$959

49% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Feb 03, 2028

Ports:

Miami → Oranjestad → Bonaire → Cabo Rojo → Ocho Rios → George Town Cayman Islands → Miami

Departs Feb 03, 2028 from Miami, Florida

Up to 3 deals

Inside From

$959

49% Off List

List Price

$1,868

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$359

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Feb 04, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Feb 04, 2028 from Miami, Florida

Up to 3 deals

Inside From

$359

44% Off List

List Price

$643

View Expanded Details

MSC Cruises MSC Seashore itinerary map

6-night caribbean cruise

Inside From

$589

46% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Feb 06, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Grand Turk → Nassau → Miami

Departs Feb 06, 2028 from Miami, Florida

Up to 3 deals

Inside From

$589

46% Off List

List Price

$1,094

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$346

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Feb 07, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Feb 07, 2028 from Miami, Florida

Up to 3 deals

Inside From

$346

43% Off List

List Price

$607

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$661

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Feb 07, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Feb 07, 2028 from Miami, Florida

Up to 1 deal

Inside From

$661

47% Off List

List Price

$1,236

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$839

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 07, 2028 View Other Dates →

Ports:

Departs Feb 07, 2028 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$839

49% Off List

List Price

$1,649

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,630

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 07, 2028 View Other Dates →

Ports:

Departs Feb 07, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,630

49% Off List

List Price

$3,208

View Expanded Details

Showing 626-650 of 1,164 results

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