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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$329

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 10, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 10, 2027 from Miami, Florida

Up to 3 deals

Inside From

$329

44% Off List

List Price

$583

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$360

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 12, 2027 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Dec 12, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$360

45% Off List

List Price

$660

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night caribbean cruise

Inside From

$899

49% Off List

MSC Cruises – MSC World Asia

Date:

Dec 12, 2027 View Other Dates →

Ports:

Departs Dec 12, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 1 deal

Inside From

$899

49% Off List

List Price

$1,768

View Expanded Details

MSC Cruises MSC Seashore itinerary map

14-night caribbean cruise

Inside From

$1,538

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 12, 2027 View Other Dates →

Ports:

Departs Dec 12, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,538

48% Off List

List Price

$2,961

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$346

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 13, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 13, 2027 from Miami, Florida

Up to 3 deals

Inside From

$346

43% Off List

List Price

$607

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$621

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 13, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Dec 13, 2027 from Miami, Florida

Up to 1 deal

Inside From

$621

46% Off List

List Price

$1,156

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$729

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 13, 2027 View Other Dates →

Ports:

Departs Dec 13, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$729

49% Off List

List Price

$1,429

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,000

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 13, 2027 View Other Dates →

Ports:

Departs Dec 13, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$2,000

49% Off List

List Price

$3,948

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 16, 2027 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Dec 16, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$349

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 17, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 17, 2027 from Miami, Florida

Up to 3 deals

Inside From

$349

44% Off List

List Price

$623

View Expanded Details

MSC Cruises MSC World America itinerary map

6-night caribbean cruise

Inside From

$859

47% Off List

MSC Cruises – MSC World America

Date:

Dec 18, 2027

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Costa Maya → Cozumel → Miami

Departs Dec 18, 2027 from Miami, Florida

Up to 3 deals

Inside From

$859

47% Off List

List Price

$1,634

View Expanded Details

MSC Cruises MSC Seashore itinerary map

8-night caribbean cruise

Inside From

$1,098

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 18, 2027 View Other Dates →

Ports:

Miami → Saint Maarten (Phillipsburg) → Saint Kitts and Nevis (Basse Terre) → Charlotte Amalie → Puerto Plata → Miami

Departs Dec 18, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,098

48% Off List

List Price

$2,106

View Expanded Details

MSC Cruises MSC Seashore itinerary map

15-night caribbean cruise

Inside From

$2,241

49% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 18, 2027

Ports:

Departs Dec 18, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,241

49% Off List

List Price

$4,404

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$370

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 19, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Dec 19, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$370

46% Off List

List Price

$680

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

11-night caribbean cruise

Inside From

$1,323

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 19, 2027

Ports:

Departs Dec 19, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,323

49% Off List

List Price

$2,586

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night caribbean cruise

Inside From

$1,499

49% Off List

MSC Cruises – MSC World Asia

Date:

Dec 19, 2027

Ports:

Departs Dec 19, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 1 deal

Inside From

$1,499

49% Off List

List Price

$2,968

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$416

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 20, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 20, 2027 from Miami, Florida

Up to 3 deals

Inside From

$416

44% Off List

List Price

$747

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$861

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 20, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Dec 20, 2027 from Miami, Florida

Up to 1 deal

Inside From

$861

47% Off List

List Price

$1,636

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$1,309

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 20, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Dec 20, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$1,309

49% Off List

List Price

$2,589

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,752

50% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 20, 2027 View Other Dates →

Ports:

Departs Dec 20, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$2,752

50% Off List

List Price

$5,452

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$951

48% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 23, 2027

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Puerto Plata → Grand Turk → Port Canaveral

Departs Dec 23, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$951

48% Off List

List Price

$1,824

View Expanded Details

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Inside From

$1,789

49% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Dec 23, 2027

Ports:

Miami → Oranjestad → Curacao → Bonaire → Cabo Rojo → Ocho Rios → Miami

Departs Dec 23, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,789

49% Off List

List Price

$3,528

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$519

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 24, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 24, 2027 from Miami, Florida

Up to 3 deals

Inside From

$519

46% Off List

List Price

$963

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$1,284

48% Off List

MSC Cruises – MSC World America

Date:

Dec 24, 2027 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Dec 24, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,284

48% Off List

List Price

$2,447

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night caribbean cruise

Inside From

$1,729

50% Off List

MSC Cruises – MSC World Asia

Date:

Dec 25, 2027

Ports:

Departs Dec 25, 2027 from Fort de France, Martinique

Up to 1 deal

Inside From

$1,729

50% Off List

List Price

$3,428

View Expanded Details

Showing 576-600 of 1,164 results

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