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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$368

32% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Sep 23, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Sep 23, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$368

32% Off List

List Price

$543

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,268

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 02, 2027 View Other Dates →

Ports:

Departs Oct 02, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,268

45% Off List

List Price

$2,298

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$719

47% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Oct 08, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Oct 08, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$719

47% Off List

List Price

$1,349

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,197

48% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 09, 2027 View Other Dates →

Ports:

Departs Oct 09, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,197

48% Off List

List Price

$2,298

View Expanded Details

MSC Cruises MSC Poesia itinerary map

5-night caribbean cruise

Inside From

$449

50% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 16, 2027

Ports:

Miami → George Town Cayman Islands → Ocho Rios → Miami

Departs Oct 16, 2027 from Miami, Florida

Up to 3 deals

Inside From

$449

50% Off List

List Price

$893

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$854

44% Off List

MSC Cruises – MSC World America

Date:

Oct 16, 2027 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 16, 2027 from Miami, Florida

Up to 3 deals

Inside From

$854

44% Off List

List Price

$1,527

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,206

48% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 16, 2027 View Other Dates →

Ports:

Departs Oct 16, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,206

48% Off List

List Price

$2,300

View Expanded Details

MSC Cruises MSC Poesia itinerary map

15-night caribbean cruise

Inside From

$1,451

49% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 16, 2027

Ports:

Departs Oct 16, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,451

49% Off List

List Price

$2,824

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$322

67% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 17, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 17, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$322

67% Off List

List Price

$962

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$769

47% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Oct 22, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Oct 22, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$769

47% Off List

List Price

$1,449

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,621

48% Off List

MSC Cruises – MSC World America

Date:

Oct 23, 2027 View Other Dates →

Ports:

Departs Oct 23, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,621

48% Off List

List Price

$3,146

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$671

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 30, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Oct 30, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$671

47% Off List

List Price

$1,264

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

15-night caribbean cruise

Inside From

$1,349

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 30, 2027

Ports:

Departs Oct 30, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,349

49% Off List

List Price

$2,620

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$322

45% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 31, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 31, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$322

45% Off List

List Price

$582

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$1,153

48% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 31, 2027 View Other Dates →

Ports:

Miami → Ocho Rios → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Oct 31, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,153

48% Off List

List Price

$2,199

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$769

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Nov 05, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Nov 05, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$769

49% Off List

List Price

$1,509

View Expanded Details

MSC Cruises MSC Seashore itinerary map

9-night caribbean cruise

Inside From

$889

50% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 05, 2027

Ports:

Departs Nov 05, 2027 from Miami, Florida

Up to 3 deals

Inside From

$889

50% Off List

List Price

$1,765

View Expanded Details

MSC Cruises MSC Seashore itinerary map

15-night caribbean cruise

Inside From

$1,409

49% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 05, 2027

Ports:

Departs Nov 05, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,409

49% Off List

List Price

$2,740

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

12-night caribbean cruise

Inside From

$1,053

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Nov 06, 2027

Ports:

Departs Nov 06, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,053

49% Off List

List Price

$2,061

View Expanded Details

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Inside From

$899

49% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Nov 11, 2027

Ports:

Miami → Bonaire → Oranjestad → Cabo Rojo → Ocho Rios → George Town Cayman Islands → Miami

Departs Nov 11, 2027 from Miami, Florida

Up to 3 deals

Inside From

$899

49% Off List

List Price

$1,748

View Expanded Details

MSC Cruises MSC Opera itinerary map

4-night caribbean cruise

Suite From

$996

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Nov 11, 2027 View Other Dates →

Ports:

Bridgetown → Fort de France → Pointe-a-Pitre → Road Town (Tortola) British Virgin Islands → La Romana

Departs Nov 11, 2027 from Bridgetown, Barbados

Up to 2 deals

Suite From

$996

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,141

47% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Nov 11, 2027

Ports:

Departs Nov 11, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,141

47% Off List

List Price

$4,076

View Expanded Details

MSC Cruises MSC Opera itinerary map

3-night caribbean cruise

Inside From

$266

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Nov 12, 2027

Ports:

Fort de France → Pointe-a-Pitre → Road Town (Tortola) British Virgin Islands → La Romana

Departs Nov 12, 2027 from Fort de France, Martinique

Up to 2 deals

Inside From

$266

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$1,217

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Nov 13, 2027

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Nov 13, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,217

48% Off List

List Price

$2,356

View Expanded Details

MSC Cruises MSC Seashore itinerary map

6-night caribbean cruise

Inside From

$539

46% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 14, 2027

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Nassau → Miami

Departs Nov 14, 2027 from Miami, Florida

Up to 3 deals

Inside From

$539

46% Off List

List Price

$994

View Expanded Details

Showing 526-550 of 1,164 results

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