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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seashore itinerary map

14-night caribbean cruise

Inside From

$1,328

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 14, 2027

Ports:

Departs Nov 14, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,328

48% Off List

List Price

$2,541

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$326

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Nov 15, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Nov 15, 2027 from Miami, Florida

Up to 3 deals

Inside From

$326

43% Off List

List Price

$567

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Nov 18, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Nov 18, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

10-night caribbean cruise

Inside From

$996

48% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Nov 18, 2027

Ports:

Departs Nov 18, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$996

48% Off List

List Price

$1,932

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$339

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Nov 19, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Nov 19, 2027 from Miami, Florida

Up to 3 deals

Inside From

$339

44% Off List

List Price

$603

View Expanded Details

MSC Cruises MSC World Asia itinerary map

11-night caribbean cruise

Inside From

$1,569

49% Off List

MSC Cruises – MSC World Asia

Date:

Nov 19, 2027

Ports:

Departs Nov 19, 2027 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,569

49% Off List

List Price

$3,068

View Expanded Details

MSC Cruises MSC Seashore itinerary map

8-night caribbean cruise

Inside From

$848

47% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 20, 2027

Ports:

Miami → Puerto Plata → Charlotte Amalie → Saint Johns → Saint Maarten (Phillipsburg) → Miami

Departs Nov 20, 2027 from Miami, Florida

Up to 3 deals

Inside From

$848

47% Off List

List Price

$1,606

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$1,117

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Nov 20, 2027 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Grand Turk → Puerto Plata → Nassau → Port Canaveral

Departs Nov 20, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,117

48% Off List

List Price

$2,156

View Expanded Details

MSC Cruises MSC Seashore itinerary map

15-night caribbean cruise

Inside From

$1,481

49% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 20, 2027

Ports:

Departs Nov 20, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,481

49% Off List

List Price

$2,884

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$456

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Nov 22, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Nov 22, 2027 from Miami, Florida

Up to 3 deals

Inside From

$456

45% Off List

List Price

$827

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$369

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Nov 26, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Nov 26, 2027 from Miami, Florida

Up to 3 deals

Inside From

$369

44% Off List

List Price

$663

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night caribbean cruise

Inside From

$919

49% Off List

MSC Cruises – MSC World Asia

Date:

Nov 27, 2027 View Other Dates →

Ports:

Departs Nov 27, 2027 from Fort de France, Martinique

Up to 1 deal

Inside From

$919

49% Off List

List Price

$1,808

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$648

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Nov 29, 2027 View Other Dates →

Ports:

Departs Nov 29, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$648

49% Off List

List Price

$1,267

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,370

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Nov 29, 2027 View Other Dates →

Ports:

Departs Nov 29, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$1,370

49% Off List

List Price

$2,688

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 02, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Dec 02, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$349

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 03, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 03, 2027 from Miami, Florida

Up to 3 deals

Inside From

$349

44% Off List

List Price

$623

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$848

47% Off List

MSC Cruises – MSC World America

Date:

Dec 04, 2027 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Dec 04, 2027 from Miami, Florida

Up to 3 deals

Inside From

$848

47% Off List

List Price

$1,610

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$339

48% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 05, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Dec 05, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$339

48% Off List

List Price

$648

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$535

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Dec 05, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Dec 05, 2027 from Galveston, Texas

Up to 3 deals

Inside From

$535

49% Off List

List Price

$1,055

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$659

47% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 05, 2027

Ports:

Miami → Saint Johns → Charlotte Amalie → Puerto Plata → Miami

Departs Dec 05, 2027 from Miami, Florida

Up to 3 deals

Inside From

$659

47% Off List

List Price

$1,254

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night caribbean cruise

Inside From

$889

49% Off List

MSC Cruises – MSC World Asia

Date:

Dec 05, 2027 View Other Dates →

Ports:

Departs Dec 05, 2027 from Pointe-a-Pitre, Guadeloupe

Up to 1 deal

Inside From

$889

49% Off List

List Price

$1,748

View Expanded Details

MSC Cruises MSC Seashore itinerary map

13-night caribbean cruise

Inside From

$1,121

47% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 05, 2027

Ports:

Departs Dec 05, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,121

47% Off List

List Price

$2,131

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$346

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 06, 2027 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 06, 2027 from Miami, Florida

Up to 3 deals

Inside From

$346

43% Off List

List Price

$607

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$759

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 06, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Dec 06, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$759

49% Off List

List Price

$1,489

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 09, 2027 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Dec 09, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

Showing 551-575 of 1,164 results

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