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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$473

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 23, 2028 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Mar 23, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$473

46% Off List

List Price

$876

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$409

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 24, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Mar 24, 2028 from Miami, Florida

Up to 3 deals

Inside From

$409

45% Off List

List Price

$743

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$530

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 26, 2028 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Mar 26, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$530

47% Off List

List Price

$1,000

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$675

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Mar 26, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Mar 26, 2028 from Galveston, Texas

Up to 3 deals

Inside From

$675

49% Off List

List Price

$1,335

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$1,133

48% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Mar 26, 2028 View Other Dates →

Ports:

Miami → Ocho Rios → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Mar 26, 2028 from Miami, Florida

Up to 3 deals

Inside From

$1,133

48% Off List

List Price

$2,159

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$466

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 27, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Mar 27, 2028 from Miami, Florida

Up to 3 deals

Inside From

$466

45% Off List

List Price

$847

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$791

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 27, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Mar 27, 2028 from Miami, Florida

Up to 1 deal

Inside From

$791

47% Off List

List Price

$1,496

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,290

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 27, 2028 View Other Dates →

Ports:

Departs Mar 27, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,290

49% Off List

List Price

$2,528

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$443

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Mar 30, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Mar 30, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$443

46% Off List

List Price

$816

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$389

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 31, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Mar 31, 2028 from Miami, Florida

Up to 3 deals

Inside From

$389

45% Off List

List Price

$703

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night caribbean cruise

Inside From

$1,049

49% Off List

MSC Cruises – MSC World Asia

Date:

Apr 01, 2028 View Other Dates →

Ports:

Departs Apr 01, 2028 from Fort de France, Martinique

Up to 1 deal

Inside From

$1,049

49% Off List

List Price

$2,068

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$2,000

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Apr 01, 2028 View Other Dates →

Ports:

Departs Apr 01, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$2,000

48% Off List

List Price

$3,856

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$470

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 02, 2028 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Apr 02, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$470

47% Off List

List Price

$880

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$665

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Apr 02, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Apr 02, 2028 from Galveston, Texas

Up to 3 deals

Inside From

$665

49% Off List

List Price

$1,315

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$436

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 03, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Apr 03, 2028 from Miami, Florida

Up to 3 deals

Inside From

$436

45% Off List

List Price

$787

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$749

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 03, 2028 View Other Dates →

Ports:

Departs Apr 03, 2028 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$749

49% Off List

List Price

$1,469

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$978

48% Off List

MSC Cruises – MSC World America

Date:

Apr 08, 2028 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 08, 2028 from Miami, Florida

Up to 2 deals

Inside From

$978

48% Off List

List Price

$1,870

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$695

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Apr 09, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Apr 09, 2028 from Galveston, Texas

Up to 3 deals

Inside From

$695

49% Off List

List Price

$1,375

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$486

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 10, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Apr 10, 2028 from Miami, Florida

Up to 3 deals

Inside From

$486

45% Off List

List Price

$887

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$811

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 10, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Apr 10, 2028 from Miami, Florida

Up to 1 deal

Inside From

$811

47% Off List

List Price

$1,536

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$929

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 10, 2028 View Other Dates →

Ports:

Departs Apr 10, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$929

49% Off List

List Price

$1,829

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,820

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 10, 2028 View Other Dates →

Ports:

Departs Apr 10, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,820

49% Off List

List Price

$3,570

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$443

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 13, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Apr 13, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$443

46% Off List

List Price

$816

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,938

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 13, 2028 View Other Dates →

Ports:

Departs Apr 13, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,938

49% Off List

List Price

$3,806

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$419

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 14, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Apr 14, 2028 from Miami, Florida

Up to 3 deals

Inside From

$419

45% Off List

List Price

$763

View Expanded Details

Showing 701-725 of 1,164 results

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