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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$508

65% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 17, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 17, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$508

65% Off List

List Price

$1,455

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,468

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Oct 28, 2027 View Other Dates →

Ports:

Departs Oct 28, 2027 from Bridgetown, Barbados

Up to 3 deals

Inside From

$1,468

49% Off List

List Price

$2,884

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Oceanview From

$1,117

42% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Oct 29, 2027 View Other Dates →

Ports:

Departs Oct 29, 2027 from Fort de France, Martinique

Up to 3 deals

Oceanview From

$1,117

42% Off List

List Price

$1,941

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$2,079

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Nov 20, 2027

Ports:

Departs Nov 20, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$2,079

48% Off List

List Price

$4,014

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$785

50% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Nov 21, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Nov 21, 2027 from Galveston, Texas

Up to 3 deals

Inside From

$785

50% Off List

List Price

$1,555

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,181

48% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Nov 21, 2027

Ports:

Departs Nov 21, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,181

48% Off List

List Price

$4,156

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$907

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Nov 27, 2027

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Cozumel → Costa Maya → Port Canaveral

Departs Nov 27, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$907

48% Off List

List Price

$1,736

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,872

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Nov 27, 2027

Ports:

Departs Nov 27, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,872

48% Off List

List Price

$3,600

View Expanded Details

MSC Cruises MSC Seashore itinerary map

14-night caribbean cruise

Inside From

$1,415

48% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Nov 28, 2027

Ports:

Departs Nov 28, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,415

48% Off List

List Price

$2,715

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,001

47% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Dec 02, 2027

Ports:

Departs Dec 02, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,001

47% Off List

List Price

$3,796

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,872

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Dec 04, 2027 View Other Dates →

Ports:

Departs Dec 04, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,872

48% Off List

List Price

$3,600

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

15-night caribbean cruise

Inside From

$2,226

49% Off List

MSC Cruises – MSC World Atlantic

Date:

Dec 11, 2027

Ports:

Departs Dec 11, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$2,226

49% Off List

List Price

$4,374

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,811

48% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Dec 12, 2027

Ports:

Departs Dec 12, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,811

48% Off List

List Price

$5,416

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

15-night caribbean cruise

Inside From

$3,009

49% Off List

MSC Cruises – MSC World Atlantic

Date:

Dec 18, 2027

Ports:

Departs Dec 18, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$3,009

49% Off List

List Price

$5,940

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$1,159

49% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 26, 2027

Ports:

Miami → Grand Turk → Puerto Plata → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 26, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,159

49% Off List

List Price

$2,254

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

13-night caribbean cruise

Inside From

$2,589

49% Off List

MSC Cruises – MSC World Atlantic

Date:

Dec 26, 2027

Ports:

Departs Dec 26, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$2,589

49% Off List

List Price

$5,067

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

10-night caribbean cruise

Inside From

$1,516

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 30, 2027

Ports:

Departs Dec 30, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,516

49% Off List

List Price

$2,972

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,772

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Jan 08, 2028 View Other Dates →

Ports:

Departs Jan 08, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,772

48% Off List

List Price

$3,400

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$390

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 09, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jan 09, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$390

46% Off List

List Price

$720

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$383

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 13, 2028

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Jan 13, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$383

45% Off List

List Price

$696

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,780

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Jan 15, 2028 View Other Dates →

Ports:

Departs Jan 15, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,780

48% Off List

List Price

$3,416

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,802

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Jan 29, 2028 View Other Dates →

Ports:

Departs Jan 29, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,802

48% Off List

List Price

$3,460

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$977

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Feb 12, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Grand Turk → Puerto Plata → Nassau → Port Canaveral

Departs Feb 12, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$977

48% Off List

List Price

$1,876

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,902

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Feb 12, 2028 View Other Dates →

Ports:

Departs Feb 12, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,902

48% Off List

List Price

$3,660

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,902

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Feb 19, 2028 View Other Dates →

Ports:

Departs Feb 19, 2028 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,902

48% Off List

List Price

$3,660

View Expanded Details

Showing 176-200 of 1,179 results

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