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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$869

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 19, 2027 View Other Dates →

Ports:

Departs Jul 19, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$869

51% Off List

List Price

$1,762

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,048

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 22, 2027 View Other Dates →

Ports:

Departs Jul 22, 2027 from Bridgetown, Barbados

Up to 3 deals

Inside From

$2,048

48% Off List

List Price

$3,964

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$678

65% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jul 25, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jul 25, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$678

65% Off List

List Price

$1,915

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$825

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jul 26, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Jul 26, 2027 from Miami, Florida

Up to 1 deal

Inside From

$825

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$631

65% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 01, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 01, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$631

65% Off List

List Price

$1,815

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$446

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 02, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Aug 02, 2027 from Miami, Florida

Up to 3 deals

Inside From

$446

46% Off List

List Price

$829

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,998

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 05, 2027 View Other Dates →

Ports:

Departs Aug 05, 2027 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,998

49% Off List

List Price

$3,944

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$623

61% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 08, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 08, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$623

61% Off List

List Price

$1,615

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$1,127

43% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 13, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Aug 13, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$1,127

43% Off List

List Price

$1,961

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$615

59% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 14, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Aug 14, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$615

59% Off List

List Price

$1,486

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$402

44% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Aug 15, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Aug 15, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$402

44% Off List

List Price

$722

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,938

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 19, 2027 View Other Dates →

Ports:

Departs Aug 19, 2027 from Bridgetown, Barbados

Up to 3 deals

Inside From

$1,938

48% Off List

List Price

$3,710

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$497

57% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Sep 04, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Sep 04, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$497

57% Off List

List Price

$1,146

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$511

64% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 05, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 05, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$511

64% Off List

List Price

$1,415

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$495

53% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Sep 11, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Sep 11, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$495

53% Off List

List Price

$1,046

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$472

76% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Sep 18, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Sep 18, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$472

76% Off List

List Price

$1,986

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,188

61% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Sep 18, 2027 View Other Dates →

Ports:

Departs Sep 18, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,188

61% Off List

List Price

$3,080

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,650

27% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Sep 25, 2027 View Other Dates →

Ports:

Departs Sep 25, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,650

27% Off List

List Price

$2,260

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$517

63% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 26, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 26, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$517

63% Off List

List Price

$1,415

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$664

47% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Sep 27, 2027 View Other Dates →

Ports:

Departs Sep 27, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$664

47% Off List

List Price

$1,242

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Oceanview From

$1,738

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Sep 30, 2027 View Other Dates →

Ports:

Departs Sep 30, 2027 from Bridgetown, Barbados

Up to 1 deal

Oceanview From

$1,738

48% Off List

List Price

$3,336

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$531

51% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 09, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Oct 09, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$531

51% Off List

List Price

$1,084

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$525

64% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 10, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 10, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$525

64% Off List

List Price

$1,455

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Oceanview From

$1,748

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Oct 14, 2027 View Other Dates →

Ports:

Departs Oct 14, 2027 from Bridgetown, Barbados

Up to 3 deals

Oceanview From

$1,748

49% Off List

List Price

$3,444

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$521

56% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Oct 16, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Oct 16, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$521

56% Off List

List Price

$1,186

View Expanded Details

Showing 151-175 of 1,179 results

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