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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,848

50% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 26, 2027 View Other Dates →

Ports:

Departs Feb 26, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$1,848

50% Off List

List Price

$3,681

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$790

66% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Feb 27, 2027 View Other Dates →

Ports:

Departs Feb 27, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$790

66% Off List

List Price

$2,356

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,755

34% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Mar 07, 2027 View Other Dates →

Ports:

Departs Mar 07, 2027 from Miami, Florida

Up to 2 deals

Inside From

$2,755

34% Off List

List Price

$4,156

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Oceanview From

$779

53% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 08, 2027 View Other Dates →

Ports:

Departs Mar 08, 2027 from La Romana, Dominican Republic

Up to 2 deals

Oceanview From

$779

53% Off List

List Price

$1,673

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

8-night caribbean cruise

Inside From

$781

47% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Mar 13, 2027

Ports:

Miami → Saint Maarten (Phillipsburg) → Saint Johns → Charlotte Amalie → Nassau → Miami

Departs Mar 13, 2027 from Miami, Florida

Up to 3 deals

Inside From

$781

47% Off List

List Price

$1,486

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,830

47% Off List

MSC Cruises – MSC World America

Date:

Mar 13, 2027 View Other Dates →

Ports:

Departs Mar 13, 2027 from Miami, Florida

Up to 2 deals

Inside From

$1,830

47% Off List

List Price

$3,446

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$429

49% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Mar 14, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Mar 14, 2027 from Port Canaveral, Florida

Up to 1 deal

Inside From

$429

49% Off List

List Price

$842

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,465

44% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Mar 18, 2027 View Other Dates →

Ports:

Departs Mar 18, 2027 from Miami, Florida

Up to 2 deals

Inside From

$2,465

44% Off List

List Price

$4,416

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

6-night caribbean cruise

Inside From

$521

61% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Mar 21, 2027 View Other Dates →

Ports:

Miami → Grand Turk → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Mar 21, 2027 from Miami, Florida

Up to 3 deals

Inside From

$521

61% Off List

List Price

$1,334

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,506

47% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Mar 21, 2027 View Other Dates →

Ports:

Departs Mar 21, 2027 from Miami, Florida

Up to 3 deals

Inside From

$1,506

47% Off List

List Price

$2,817

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$393

59% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Mar 22, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Mar 22, 2027 from Miami, Florida

Up to 3 deals

Inside From

$393

59% Off List

List Price

$947

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$949

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 22, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Mar 22, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$949

51% Off List

List Price

$1,944

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$431

68% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Mar 28, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Mar 28, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$431

68% Off List

List Price

$1,335

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$1,170

49% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Mar 28, 2027 View Other Dates →

Ports:

Miami → Ocho Rios → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Mar 28, 2027 from Miami, Florida

Up to 2 deals

Inside From

$1,170

49% Off List

List Price

$2,309

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$769

52% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 05, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Apr 05, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$769

52% Off List

List Price

$1,601

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$313

53% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 09, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 09, 2027 from Miami, Florida

Up to 2 deals

Inside From

$313

53% Off List

List Price

$663

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,028

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 15, 2027 View Other Dates →

Ports:

Departs Apr 15, 2027 from Bridgetown, Barbados

Up to 3 deals

Inside From

$2,028

49% Off List

List Price

$4,004

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$313

73% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 16, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 16, 2027 from Miami, Florida

Up to 2 deals

Inside From

$313

73% Off List

List Price

$1,163

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$471

60% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 17, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Apr 17, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$471

60% Off List

List Price

$1,184

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$329

52% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 19, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 19, 2027 from Miami, Florida

Up to 2 deals

Inside From

$329

52% Off List

List Price

$687

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$358

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Apr 23, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Apr 23, 2027 from Miami, Florida

Up to 2 deals

Inside From

$358

46% Off List

List Price

$663

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$959

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 23, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Apr 23, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$959

51% Off List

List Price

$1,967

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,152

55% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Apr 24, 2027 View Other Dates →

Ports:

Departs Apr 24, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,152

55% Off List

List Price

$2,558

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$503

67% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Apr 25, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Apr 25, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$503

67% Off List

List Price

$1,535

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$555

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 03, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs May 03, 2027 from Miami, Florida

Up to 1 deal

Inside From

$555

View Expanded Details

Showing 101-125 of 1,178 results

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