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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$865

50% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 03, 2027 View Other Dates →

Ports:

Departs May 03, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$865

50% Off List

List Price

$1,718

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,196

56% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 08, 2027 View Other Dates →

Ports:

Departs May 08, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,196

56% Off List

List Price

$2,700

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$626

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 10, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs May 10, 2027 from Miami, Florida

Up to 1 deal

Inside From

$626

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,159

57% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 15, 2027 View Other Dates →

Ports:

Departs May 15, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,159

57% Off List

List Price

$2,700

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,229

56% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 22, 2027 View Other Dates →

Ports:

Departs May 22, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,229

56% Off List

List Price

$2,800

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Oceanview From

$1,998

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 27, 2027 View Other Dates →

Ports:

Departs May 27, 2027 from Bridgetown, Barbados

Up to 3 deals

Oceanview From

$1,998

49% Off List

List Price

$3,944

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,399

52% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 29, 2027 View Other Dates →

Ports:

Departs May 29, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,399

52% Off List

List Price

$2,900

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$849

47% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 04, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Jun 04, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$849

47% Off List

List Price

$1,609

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$639

54% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 05, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Jun 05, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$639

54% Off List

List Price

$1,386

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,588

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 05, 2027 View Other Dates →

Ports:

Departs Jun 05, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,588

46% Off List

List Price

$2,960

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$769

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 07, 2027 View Other Dates →

Ports:

Departs Jun 07, 2027 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$769

48% Off List

List Price

$1,491

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Oceanview From

$2,078

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 10, 2027 View Other Dates →

Ports:

Departs Jun 10, 2027 from Bridgetown, Barbados

Up to 2 deals

Oceanview From

$2,078

49% Off List

List Price

$4,096

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,570

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 12, 2027 View Other Dates →

Ports:

Departs Jun 12, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,570

49% Off List

List Price

$3,100

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,521

46% Off List

MSC Cruises – MSC World America

Date:

Jun 12, 2027 View Other Dates →

Ports:

Departs Jun 12, 2027 from Miami, Florida

Up to 3 deals

Inside From

$2,521

46% Off List

List Price

$4,646

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,619

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 19, 2027 View Other Dates →

Ports:

Departs Jun 19, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,619

49% Off List

List Price

$3,200

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,658

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 24, 2027 View Other Dates →

Ports:

Departs Jun 24, 2027 from Bridgetown, Barbados

Up to 3 deals

Inside From

$1,658

49% Off List

List Price

$3,264

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$979

44% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 25, 2027 View Other Dates →

Ports:

Departs Jun 25, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$979

44% Off List

List Price

$1,743

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$695

66% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Jun 27, 2027 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Jun 27, 2027 from Galveston, Texas

Up to 2 deals

Inside From

$695

66% Off List

List Price

$2,015

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$506

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 28, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jun 28, 2027 from Miami, Florida

Up to 3 deals

Inside From

$506

44% Off List

List Price

$909

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$1,027

46% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 02, 2027 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Jul 02, 2027 from Fort de France, Martinique

Up to 3 deals

Inside From

$1,027

46% Off List

List Price

$1,887

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$2,098

48% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 08, 2027 View Other Dates →

Ports:

Departs Jul 08, 2027 from Bridgetown, Barbados

Up to 1 deal

Inside From

$2,098

48% Off List

List Price

$4,056

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$718

57% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 10, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Cozumel → Costa Maya → Port Canaveral

Departs Jul 10, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$718

57% Off List

List Price

$1,686

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$486

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jul 12, 2027 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Jul 12, 2027 from Miami, Florida

Up to 3 deals

Inside From

$486

44% Off List

List Price

$869

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$684

57% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 17, 2027 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Jul 17, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$684

57% Off List

List Price

$1,586

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,699

49% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 17, 2027 View Other Dates →

Ports:

Departs Jul 17, 2027 from Port Canaveral, Florida

Up to 3 deals

Inside From

$1,699

49% Off List

List Price

$3,300

View Expanded Details

Showing 126-150 of 1,179 results

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