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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Oceanview From

$769

50% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 07, 2026 View Other Dates →

Ports:

Departs Dec 07, 2026 from La Romana, Dominican Republic

Up to 2 deals

Oceanview From

$769

50% Off List

List Price

$1,536

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$916

62% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 12, 2026 View Other Dates →

Ports:

Departs Dec 12, 2026 from Port Canaveral, Florida

Up to 2 deals

Inside From

$916

62% Off List

List Price

$2,442

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$219

58% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Dec 13, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Dec 13, 2026 from Port Canaveral, Florida

Up to 2 deals

Inside From

$219

58% Off List

List Price

$516

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

6-night caribbean cruise

Inside From

$269

64% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Dec 13, 2026 View Other Dates →

Ports:

Miami → Grand Turk → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 13, 2026 from Miami, Florida

Up to 4 deals

Inside From

$269

64% Off List

List Price

$754

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,495

59% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Dec 13, 2026

Ports:

Departs Dec 13, 2026 from Miami, Florida

Up to 2 deals

Inside From

$2,495

59% Off List

List Price

$6,074

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$549

52% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 14, 2026 View Other Dates →

Ports:

Departs Dec 14, 2026 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$549

52% Off List

List Price

$1,154

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Oceanview From

$640

39% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 14, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Nassau → Miami

Departs Dec 14, 2026 from Miami, Florida

Up to 3 deals

Oceanview From

$640

39% Off List

List Price

$1,056

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Balcony From

$429

39% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 18, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Dec 18, 2026 from Miami, Florida

Up to 2 deals

Balcony From

$429

39% Off List

List Price

$703

View Expanded Details

MSC Cruises MSC Seaside itinerary map

10-night caribbean cruise

Balcony From

$1,491

50% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 18, 2026

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami → Puerto Plata → San Juan → Miami

Departs Dec 18, 2026 from Miami, Florida

Up to 2 deals

Balcony From

$1,491

50% Off List

List Price

$2,986

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

7-night caribbean cruise

Inside From

$507

66% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 19, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Puerto Plata → Port Canaveral

Departs Dec 19, 2026 from Port Canaveral, Florida

Up to 2 deals

Inside From

$507

66% Off List

List Price

$1,502

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

8-night caribbean cruise

Inside From

$647

67% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Dec 19, 2026 View Other Dates →

Ports:

Departs Dec 19, 2026 from Miami, Florida

Up to 3 deals

Inside From

$647

67% Off List

List Price

$1,986

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,498

60% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 19, 2026 View Other Dates →

Ports:

Departs Dec 19, 2026 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,498

60% Off List

List Price

$3,790

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$2,036

48% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Dec 19, 2026 View Other Dates →

Ports:

Departs Dec 19, 2026 from Miami, Florida

Up to 3 deals

Inside From

$2,036

48% Off List

List Price

$3,937

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$689

65% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 21, 2026 View Other Dates →

Ports:

Departs Dec 21, 2026 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$689

65% Off List

List Price

$1,956

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Balcony From

$982

59% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 21, 2026

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Dec 21, 2026 from Miami, Florida

Up to 2 deals

Balcony From

$982

59% Off List

List Price

$2,378

View Expanded Details

MSC Cruises MSC Poesia itinerary map

22-night caribbean cruise

Inside From

$2,708

56% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Dec 23, 2026

Ports:

Departs Dec 23, 2026 from Miami, Florida

Up to 2 deals

Inside From

$2,708

56% Off List

List Price

$6,090

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$1,414

57% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Dec 26, 2026 View Other Dates →

Ports:

Departs Dec 26, 2026 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,414

57% Off List

List Price

$3,312

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

6-night caribbean cruise

Inside From

$919

58% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Dec 27, 2026 View Other Dates →

Ports:

Miami → Grand Turk → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Dec 27, 2026 from Miami, Florida

Up to 3 deals

Inside From

$919

58% Off List

List Price

$2,194

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$1,135

44% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Dec 27, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Dec 27, 2026 from Galveston, Texas

Up to 1 deal

Inside From

$1,135

44% Off List

List Price

$2,035

View Expanded Details

MSC Cruises MSC Meraviglia itinerary map

14-night caribbean cruise

Inside From

$1,636

48% Off List

MSC Cruises – MSC Meraviglia

3.889 Reviews

Date:

Dec 27, 2026 View Other Dates →

Ports:

Departs Dec 27, 2026 from Miami, Florida

Up to 3 deals

Inside From

$1,636

48% Off List

List Price

$3,137

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$1,112

56% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Dec 28, 2026

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Falmouth → George Town Cayman Islands → Cozumel → Miami

Departs Dec 28, 2026 from Miami, Florida

Up to 2 deals

Inside From

$1,112

56% Off List

List Price

$2,532

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$1,267

54% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Dec 28, 2026 View Other Dates →

Ports:

Departs Dec 28, 2026 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$1,267

54% Off List

List Price

$2,770

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

14-night caribbean cruise

Inside From

$810

60% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jan 02, 2027 View Other Dates →

Ports:

Departs Jan 02, 2027 from Port Canaveral, Florida

Up to 2 deals

Inside From

$810

60% Off List

List Price

$2,036

View Expanded Details

MSC Cruises MSC Poesia itinerary map

11-night caribbean cruise

Inside From

$678

66% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Jan 03, 2027 View Other Dates →

Ports:

Miami → Montego Bay → Cartagena → Colon → Puerto Limon → Roatan → Belize City → Miami

Departs Jan 03, 2027 from Miami, Florida

Up to 2 deals

Inside From

$678

66% Off List

List Price

$2,009

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Inside From

$2,155

46% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Jan 03, 2027

Ports:

Departs Jan 03, 2027 from Miami, Florida

Up to 2 deals

Inside From

$2,155

46% Off List

List Price

$3,956

View Expanded Details

Showing 51-75 of 1,178 results

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