Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best Mediterranean Cruises

Showing 426-450 of 7,059 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
9-night mediterranean cruise
$4,680
Silversea – Silver Nova
5.0 (5)
Departs Nov 30, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
7-night mediterranean cruise
$1,600
62% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Dec 02, 2026 from Rome (Civitavecchia), Italy
Up to 6 deals including an Avoya Exclusive
Secret Rate
14-night mediterranean cruise
$5,040
76% Off List
Regent Cruises – Seven Seas Navigator
4.3 (72)
Departs Dec 07, 2026 from Barcelona, Spain
14-night mediterranean cruise
$3,425
62% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Dec 21, 2026 from Lisbon, Portugal
Up to 6 deals including an Avoya Exclusive
Secret Rate
14-night mediterranean cruise
$7,480
70% Off List
Regent Cruises – Seven Seas Navigator
4.3 (72)
Departs Dec 21, 2026 from Rome (Civitavecchia), Italy
Up to 1 deal
10-night mediterranean cruise
$2,190
59% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Jan 04, 2027 from Rome (Civitavecchia), Italy
Up to 6 deals including an Avoya Exclusive
Secret Rate
8-night mediterranean cruise
$2,170
55% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Mar 03, 2027 from Lisbon, Portugal
Up to 4 deals including an Avoya Exclusive
Secret Rate
9-night mediterranean cruise
$2,285
52% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Mar 29, 2027 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
Secret Rate
10-night mediterranean cruise
$2,762
52% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Apr 07, 2027 from Istanbul, Turkey
Up to 3 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$2,699
50% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Apr 10, 2027 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$3,599
50% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Apr 16, 2027 from Barcelona, Spain
Up to 4 deals including an Avoya Exclusive
9-night mediterranean cruise
$2,475
52% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Apr 17, 2027 from Venice, Italy
Up to 3 deals including an Avoya Exclusive
Secret Rate
11-night mediterranean cruise
$3,249
52% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Apr 17, 2027 from Trieste, Italy
Up to 4 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,214
Princess Cruises – Sun Princess
4.3 (7)
Departs Apr 18, 2027 from Rome (Civitavecchia), Italy
Up to 7 deals including an Avoya Exclusive
Secret Rate
22-night mediterranean cruise
$18,549
60% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Apr 18, 2027 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
11-night mediterranean cruise
$2,022
Holland America – Oosterdam
4.2 (212)
Departs Apr 23, 2027 from Barcelona, Spain
Up to 3 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$2,997
52% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Apr 23, 2027 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
Secret Rate
9-night mediterranean cruise
$2,617
52% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Apr 26, 2027 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
Secret Rate
12-night mediterranean cruise
$3,760
52% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Apr 28, 2027 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
Secret Rate
22-night mediterranean cruise
$2,750
Princess Cruises – Regal Princess
4.4 (285)
Departs Apr 30, 2027 from Southampton, United Kingdom
Secret Rate
7-night mediterranean cruise
$2,999
50% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Apr 30, 2027 from Trieste, Italy
Up to 3 deals including an Avoya Exclusive
29-night mediterranean cruise
$3,787
Princess Cruises – Regal Princess
4.4 (285)
Departs Apr 30, 2027 from Southampton, United Kingdom
Secret Rate
37-night mediterranean cruise
$5,000
Princess Cruises – Regal Princess
4.4 (285)
Departs Apr 30, 2027 from Southampton, United Kingdom
Secret Rate
46-night mediterranean cruise
$6,226
Princess Cruises – Regal Princess
4.4 (285)
Departs Apr 30, 2027 from Southampton, United Kingdom
Secret Rate
56-night mediterranean cruise
$7,782
Princess Cruises – Regal Princess
4.4 (285)
Departs Apr 30, 2027 from Southampton, United Kingdom
Secret Rate

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada: 1-888-877-7042
UK: 0-800-098-8475
Australia: 1-800-651-320
International: 001-760-305-5070
Avoya Travel. Beyond The Web.®
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo