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Best Panama Canal Cruises

Showing 51-75 of 179 results
18-night panama canal cruise
Balcony From
$6,637
62% Off List
Oceania Cruises – Vista
4.737 Reviews
Departs Oct 24, 2027 from Miami, Florida
Up to 5 deals including an Avoya Exclusive
Secret Rate
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11-night panama canal cruise
Inside From
$619
Norwegian Cruise Line – Norwegian Sun
4.1156 Reviews
Departs Nov 18, 2026 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
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12-night panama canal cruise
Inside From
$683
Princess Cruises – Caribbean Princess
4.1257 Reviews
Departs Nov 23, 2026 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
Secret Rate
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11-night panama canal cruise
Inside From
$649
Norwegian Cruise Line – Norwegian Sun
4.1156 Reviews
Departs Nov 29, 2026 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
Avoya Exclusive Rate
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16-night panama canal cruise
Inside From
$1,109
Princess Cruises – Crown Princess
4.3211 Reviews
Departs Dec 03, 2026 from Los Angeles, California
Up to 4 deals including an Avoya Exclusive
Secret Rate
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11-night panama canal cruise
Inside From
$1,059
Norwegian Cruise Line – Norwegian Sun
4.1156 Reviews
Departs Dec 10, 2026 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
Avoya Exclusive Rate
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16-night panama canal cruise
Suite From
$17,949
Regent Cruises – Seven Seas Grandeur
5.04 Reviews
Departs Dec 29, 2026 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
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14-night panama canal cruise
Inside From
$1,899
Holland America – Zuiderdam
4.3157 Reviews
Departs Jan 02, 2027 from Miami, Florida
Up to 2 deals including an Avoya Exclusive
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14-night panama canal cruise
Suite From
$15,699
58% Off List
Regent Cruises – Seven Seas Splendor
4.331 Reviews
Departs Jan 12, 2027 from Miami, Florida
Up to 2 deals including an Avoya Exclusive
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12-night panama canal cruise
Inside From
$1,562
Princess Cruises – Caribbean Princess
4.1257 Reviews
Departs Feb 03, 2027 from Fort Lauderdale, Florida
Up to 5 deals including an Avoya Exclusive
Secret Rate
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16-night panama canal cruise
Inside From
$1,729
Princess Cruises – Island Princess
4.2157 Reviews
Departs Mar 02, 2027 from Los Angeles, California
Up to 5 deals including an Avoya Exclusive
Secret Rate
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20-night panama canal cruise
Balcony From
$10,299
50% Off List
Oceania Cruises – Marina
4.5399 Reviews
Departs Mar 05, 2027 from Miami, Florida
Up to 4 deals including an Avoya Exclusive
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14-night panama canal cruise
Inside From
$1,399
Holland America – Zaandam
4.5133 Reviews
Departs Mar 14, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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14-night panama canal cruise
Inside From
$2,034
Holland America – Eurodam
4.3283 Reviews
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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21-night panama canal cruise
Inside From
$2,349
Holland America – Eurodam
4.3283 Reviews
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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17-night panama canal cruise
Inside From
$1,974
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Apr 11, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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16-night panama canal cruise
Inside From
$1,809
Princess Cruises – Island Princess
4.2157 Reviews
Departs Apr 19, 2027 from Fort Lauderdale, Florida
Up to 6 deals including an Avoya Exclusive
Secret Rate
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15-night panama canal cruise
Oceanview From
$2,259
30% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 07, 2027 from San Diego, California
Up to 5 deals including Avoya Exclusives
Avoya Exclusive Rate
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11-night panama canal cruise
Inside From
$2,057
Celebrity Cruises – Celebrity Ascent
5.022 Reviews
Departs Nov 22, 2027 from Fort Lauderdale, Florida
Up to 5 deals including Avoya Exclusives
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10-night panama canal cruise
Inside From
$1,539
Norwegian Cruise Line – Norwegian Gem
4.2150 Reviews
Departs Jan 02, 2028 from Miami, Florida
Up to 5 deals including an Avoya Exclusive
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10-night panama canal cruise
Inside From
$3,349
50% Off List
Oceania Cruises – Marina
4.5399 Reviews
Departs Jan 06, 2028 from Miami, Florida
Up to 4 deals including an Avoya Exclusive
View Expanded Details
15-night panama canal cruise
Inside From
$1,919
Norwegian Cruise Line – Norwegian Encore
4.477 Reviews
Departs Jan 09, 2028 from Los Angeles, California
Up to 6 deals including an Avoya Exclusive
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16-night panama canal cruise
Inside From
$1,599
Princess Cruises – Island Princess
4.2157 Reviews
Departs Jan 14, 2028 from Fort Lauderdale, Florida
Up to 5 deals including Avoya Exclusives
Avoya Exclusive Rate
View Expanded Details
10-night panama canal cruise
Inside From
$3,099
50% Off List
Oceania Cruises – Marina
4.5399 Reviews
Departs Jan 16, 2028 from Panama City (Fuerte Amador), Panama
Up to 4 deals including an Avoya Exclusive
View Expanded Details
15-night panama canal cruise
Inside From
$1,739
Norwegian Cruise Line – Norwegian Encore
4.477 Reviews
Departs Jan 24, 2028 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
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Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

Latest Articles

Latest Articles

Why a Panama Canal Cruise Is a Must-Experience Getaway

Embark on a breathtaking Panama Canal cruise through Latin America and journey through historic waterways that offer a unique blend of maritime marvels, scenic beauty, and cultural richness. Whether it’s onboard Royal Caribbean, Carnival Cruise Line, Princess Cruises, or another remarkable cruise line, sailing through the Panama Canal is a must-experience adventure. Read on to discover what awaits when cruising through the Panama Canal.

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