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Best South America Cruises

Showing 651-675 of 826 results
31-night south america cruise
Inside From
$5,889
Cunard – Queen Anne
5.01 Reviews
Departs Mar 05, 2029 from Santiago (Valparaiso), Chile
Up to 2 deals
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33-night south america cruise
Inside From
$6,399
Cunard – Queen Anne
5.01 Reviews
Departs Mar 05, 2029 from Santiago (Valparaiso), Chile
Up to 2 deals
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11-night south america cruise + tour
Suite From
$13,997
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Mar 12, 2029 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
Secret Rate
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12-night south america cruise
Suite From
$13,999
Viking Ocean Cruises – Viking Octantis
4.79 Reviews
Departs Nov 23, 2026 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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17-night south america cruise
Balcony From
$9,699
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Dec 02, 2026 from Buenos Aires, Argentina
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8-night south america cruise
Balcony From
$1,611
50% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Dec 14, 2026 from Rio de Janeiro, Brazil
Up to 3 deals
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7-night south america cruise
Balcony From
$5,348
AmaWaterways – AmaMelodia
Departs Dec 16, 2026 from Cartagena, Colombia
Up to 2 deals
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7-night south america cruise
Balcony From
$4,249
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Dec 19, 2026 from Cartagena, Colombia
Up to 2 deals
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7-night south america cruise
Inside From
$1,519
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Dec 28, 2026 from Camboriu
Up to 2 deals
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7-night south america cruise
Balcony From
$4,349
AmaWaterways – AmaMelodia
Departs Dec 30, 2026 from Cartagena, Colombia
Up to 1 deal
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7-night south america cruise
Inside From
$1,519
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Jan 03, 2027 from Santos, Brazil
Up to 2 deals
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9-night south america cruise
Oceanview From
$2,544
35% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Jan 05, 2027 from Buenos Aires, Argentina
Up to 3 deals
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7-night south america cruise
Inside From
$1,467
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Jan 14, 2027 from Buenos Aires, Argentina
Up to 2 deals
View Expanded Details
17-night south america cruise
Balcony From
$10,899
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Jan 22, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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3-night south america cruise
Inside From
$609
MSC Cruises – MSC Divina
3.892 Reviews
Departs Jan 26, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Balcony From
$5,348
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Jan 30, 2027 from Cartagena, Colombia
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7-night south america cruise
Inside From
$1,359
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Jan 31, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Balcony From
$1,446
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 03, 2027 from Maceio
Up to 3 deals
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10-night south america cruise
Suite From
$11,050
Silversea – Silver Nova
5.05 Reviews
Departs Feb 07, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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17-night south america cruise
Balcony From
$11,099
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Feb 08, 2027 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
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3-night south america cruise
Inside From
$669
MSC Cruises – MSC Divina
3.892 Reviews
Departs Feb 12, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Inside From
$1,106
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 17, 2027 from Maceio
Up to 3 deals
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3-night south america cruise
Inside From
$659
MSC Cruises – MSC Divina
3.892 Reviews
Departs Feb 19, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Balcony From
$6,048
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Feb 20, 2027 from Barranquilla, Colombia
Up to 1 deal
View Expanded Details
4-night south america cruise
Inside From
$609
MSC Cruises – MSC Divina
3.892 Reviews
Departs Feb 25, 2027 from Santos, Brazil
Up to 2 deals
View Expanded Details
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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