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Best South America Cruises

Showing 51-75 of 825 results
14-night south america cruise
Inside From
$2,778
Celebrity Cruises – Celebrity Equinox
4.6604 Reviews
Departs Jan 14, 2029 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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14-night south america cruise
Inside From
$2,778
Celebrity Cruises – Celebrity Equinox
4.6604 Reviews
Departs Jan 28, 2029 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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14-night south america cruise
Inside From
$2,778
Celebrity Cruises – Celebrity Equinox
4.6604 Reviews
Departs Feb 11, 2029 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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14-night south america cruise
Inside From
$2,382
Celebrity Cruises – Celebrity Equinox
4.6604 Reviews
Departs Feb 25, 2029 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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18-night south america cruise
Suite From
$10,750
Silversea – Silver Nova
5.05 Reviews
Departs Mar 05, 2027 from Santiago (Valparaiso), Chile
Up to 4 deals including Avoya Exclusives
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16-night south america cruise
Inside From
$2,399
Holland America – Oosterdam
4.2213 Reviews
Departs Mar 24, 2027 from San Antonio, Chile
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,598
AmaWaterways – AmaMelodia
Departs Apr 07, 2027 from Cartagena, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,698
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Apr 10, 2027 from Cartagena, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMelodia
Departs Apr 21, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,299
AmaWaterways – AmaMelodia
Departs May 05, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,549
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs May 08, 2027 from Cartagena, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,299
AmaWaterways – AmaMelodia
Departs May 12, 2027 from Barranquilla, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,648
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs May 15, 2027 from Barranquilla, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,848
AmaWaterways – AmaMelodia
Departs May 19, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,299
AmaWaterways – AmaMelodia
Departs May 26, 2027 from Barranquilla, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,348
AmaWaterways – AmaMelodia
Departs Jun 02, 2027 from Cartagena, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,498
AmaWaterways – AmaMelodia
Departs Jun 09, 2027 from Barranquilla, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,198
AmaWaterways – AmaMelodia
Departs Jun 16, 2027 from Cartagena, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,949
AmaWaterways – AmaMelodia
Departs Aug 25, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,549
AmaWaterways – AmaMelodia
Departs Sep 01, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,299
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Sep 04, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,799
AmaWaterways – AmaMelodia
Departs Sep 08, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,799
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Sep 11, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,549
AmaWaterways – AmaMelodia
Departs Sep 15, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,549
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Sep 18, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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