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Best South America Cruises

Showing 76-100 of 825 results
7-night south america cruise
Balcony From
$4,598
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Sep 25, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,348
AmaWaterways – AmaMelodia
Departs Sep 29, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,799
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Oct 02, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,799
AmaWaterways – AmaMelodia
Departs Oct 06, 2027 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,799
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Oct 09, 2027 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,799
AmaWaterways – AmaMelodia
Departs Oct 13, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$5,348
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Oct 23, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Balcony From
$3,799
AmaWaterways – AmaMelodia
Departs Oct 27, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMelodia
Departs Nov 03, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Nov 06, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Balcony From
$4,448
AmaWaterways – AmaMelodia
Departs Nov 10, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Nov 13, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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20-night south america cruise + tour
Inside From
$6,509
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 16, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,948
AmaWaterways – AmaMelodia
Departs Nov 17, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$2,559
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 21, 2027 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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21-night south america cruise + tour
Inside From
$6,709
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 21, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,698
AmaWaterways – AmaMelodia
Departs Nov 24, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Nov 27, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMelodia
Departs Dec 01, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$5,448
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Dec 04, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
15-night south america cruise
Inside From
$2,289
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 06, 2027 from San Antonio, Chile
Up to 5 deals including an Avoya Exclusive
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20-night south america cruise + tour
Inside From
$6,239
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 06, 2027 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMelodia
Departs Dec 08, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,899
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Dec 11, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,999
AmaWaterways – AmaMelodia
Departs Dec 15, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
View Expanded Details
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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