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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Oceanview From

$759

62% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 22, 2026 View Other Dates →

Ports:

Miami → Bonaire → Oranjestad → Curacao → Cabo Rojo → Ocho Rios → Miami

Departs Oct 22, 2026 from Miami, Florida

Up to 2 deals

Oceanview From

$759

62% Off List

List Price

$2,016

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$611

55% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 01, 2027 View Other Dates →

Ports:

Departs Feb 01, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$611

55% Off List

List Price

$1,349

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$999

47% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 22, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Mar 22, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$999

47% Off List

List Price

$1,901

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$874

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 26, 2027 View Other Dates →

Ports:

Departs Apr 26, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$874

51% Off List

List Price

$1,769

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$749

50% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 24, 2027 View Other Dates →

Ports:

Departs May 24, 2027 from La Romana, Dominican Republic

Up to 3 deals

Inside From

$749

50% Off List

List Price

$1,512

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Balcony From

$322

61% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 28, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 28, 2026 from Miami, Florida

Up to 2 deals

Balcony From

$322

61% Off List

List Price

$828

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Balcony From

$528

57% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 01, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 01, 2026 from Port Canaveral, Florida

Up to 3 deals

Balcony From

$528

57% Off List

List Price

$1,231

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$964

60% Off List

MSC Cruises – MSC World America

Date:

Oct 03, 2026 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 03, 2026 from Miami, Florida

Up to 4 deals

Balcony From

$964

60% Off List

List Price

$2,399

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Balcony From

$450

73% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 04, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 04, 2026 from Galveston, Texas

Up to 3 deals

Balcony From

$450

73% Off List

List Price

$1,676

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$233

64% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 05, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 05, 2026 from Miami, Florida

Up to 3 deals

Inside From

$233

64% Off List

List Price

$643

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$598

66% Off List

MSC Cruises – MSC World America

Date:

Oct 10, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 10, 2026 from Miami, Florida

Up to 4 deals

Inside From

$598

66% Off List

List Price

$1,744

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Balcony From

$396

60% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 11, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Oct 11, 2026 from Port Canaveral, Florida

Up to 3 deals

Balcony From

$396

60% Off List

List Price

$980

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$474

65% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 11, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 11, 2026 from Galveston, Texas

Up to 3 deals

Inside From

$474

65% Off List

List Price

$1,373

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$231

62% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 12, 2026

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 12, 2026 from Miami, Florida

Up to 3 deals

Inside From

$231

62% Off List

List Price

$603

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Balcony From

$407

53% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 15, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 15, 2026 from Port Canaveral, Florida

Up to 3 deals

Balcony From

$407

53% Off List

List Price

$871

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$303

52% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 16, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 16, 2026 from Miami, Florida

Up to 3 deals

Inside From

$303

52% Off List

List Price

$633

View Expanded Details

MSC Cruises MSC Poesia itinerary map

5-night caribbean cruise

Oceanview From

$476

53% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 17, 2026 View Other Dates →

Ports:

Miami → George Town Cayman Islands → Ocho Rios → Miami

Departs Oct 17, 2026 from Miami, Florida

Up to 3 deals

Oceanview From

$476

53% Off List

List Price

$1,013

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$648

71% Off List

MSC Cruises – MSC World America

Date:

Oct 17, 2026 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 17, 2026 from Miami, Florida

Up to 4 deals

Balcony From

$648

71% Off List

List Price

$2,199

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$370

69% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 18, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 18, 2026 from Galveston, Texas

Up to 3 deals

Inside From

$370

69% Off List

List Price

$1,196

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Balcony From

$497

69% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 18, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Cozumel → Costa Maya → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 18, 2026 from Port Canaveral, Florida

Up to 2 deals

Balcony From

$497

69% Off List

List Price

$1,601

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$196

68% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 19, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 19, 2026 from Miami, Florida

Up to 3 deals

Inside From

$196

68% Off List

List Price

$603

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$327

48% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 23, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 23, 2026 from Miami, Florida

Up to 2 deals

Inside From

$327

48% Off List

List Price

$633

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$612

74% Off List

MSC Cruises – MSC World America

Date:

Oct 24, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 24, 2026 from Miami, Florida

Up to 4 deals

Balcony From

$612

74% Off List

List Price

$2,324

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$303

75% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 25, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 25, 2026 from Galveston, Texas

Up to 3 deals

Inside From

$303

75% Off List

List Price

$1,196

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Oceanview From

$317

58% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 25, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Oct 25, 2026 from Port Canaveral, Florida

Up to 2 deals

Oceanview From

$317

58% Off List

List Price

$746

View Expanded Details

Showing 1-25 of 1,506 results

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