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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Inside From

$795

56% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 22, 2026 View Other Dates →

Ports:

Miami → Bonaire → Oranjestad → Curacao → Cabo Rojo → Ocho Rios → Miami

Departs Oct 22, 2026 from Miami, Florida

Up to 4 deals

Inside From

$795

56% Off List

List Price

$1,796

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$529

61% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 01, 2027 View Other Dates →

Ports:

Departs Feb 01, 2027 from La Romana, Dominican Republic

Up to 5 deals

Inside From

$529

61% Off List

List Price

$1,349

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$709

61% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 22, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Mar 22, 2027 from La Romana, Dominican Republic

Up to 5 deals

Inside From

$709

61% Off List

List Price

$1,808

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$607

58% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 26, 2027 View Other Dates →

Ports:

Departs Apr 26, 2027 from La Romana, Dominican Republic

Up to 4 deals

Inside From

$607

58% Off List

List Price

$1,444

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$568

57% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 24, 2027 View Other Dates →

Ports:

Departs May 24, 2027 from La Romana, Dominican Republic

Up to 4 deals

Inside From

$568

57% Off List

List Price

$1,315

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$989

65% Off List

MSC Cruises – MSC World America

Date:

Aug 15, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Aug 15, 2026 from Miami, Florida

Up to 3 deals

Balcony From

$989

65% Off List

List Price

$2,864

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$327

58% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Aug 16, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 16, 2026 from Port Canaveral, Florida

Up to 4 deals

Inside From

$327

58% Off List

List Price

$780

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$415

72% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 16, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 16, 2026 from Galveston, Texas

Up to 3 deals

Inside From

$415

72% Off List

List Price

$1,473

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Balcony From

$475

50% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Aug 20, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Aug 20, 2026 from Port Canaveral, Florida

Up to 3 deals

Balcony From

$475

50% Off List

List Price

$958

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$1,108

60% Off List

MSC Cruises – MSC World America

Date:

Aug 22, 2026

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Aug 22, 2026 from Miami, Florida

Up to 3 deals

Balcony From

$1,108

60% Off List

List Price

$2,739

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$415

72% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 23, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 23, 2026 from Galveston, Texas

Up to 4 deals

Inside From

$415

72% Off List

List Price

$1,473

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$321

56% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 28, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Aug 28, 2026 from Miami, Florida

Up to 3 deals

Inside From

$321

56% Off List

List Price

$733

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$1,059

63% Off List

MSC Cruises – MSC World America

Date:

Aug 29, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Aug 29, 2026 from Miami, Florida

Up to 3 deals

Balcony From

$1,059

63% Off List

List Price

$2,844

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$317

58% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Aug 30, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 30, 2026 from Port Canaveral, Florida

Up to 4 deals

Inside From

$317

58% Off List

List Price

$760

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$397

73% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 30, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 30, 2026 from Galveston, Texas

Up to 4 deals

Inside From

$397

73% Off List

List Price

$1,453

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$365

51% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Sep 03, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Sep 03, 2026 from Port Canaveral, Florida

Up to 3 deals

Inside From

$365

51% Off List

List Price

$751

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$628

12% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 04, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 04, 2026 from Miami, Florida

Up to 3 deals

Inside From

$628

12% Off List

List Price

$713

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$622

63% Off List

MSC Cruises – MSC World America

Date:

Sep 05, 2026 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 05, 2026 from Miami, Florida

Up to 3 deals

Inside From

$622

63% Off List

List Price

$1,699

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$374

72% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 06, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 06, 2026 from Galveston, Texas

Up to 4 deals

Inside From

$374

72% Off List

List Price

$1,353

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$471

57% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Sep 06, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Cozumel → Costa Maya → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Sep 06, 2026 from Port Canaveral, Florida

Up to 3 deals

Inside From

$471

57% Off List

List Price

$1,101

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$287

58% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 07, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 07, 2026 from Miami, Florida

Up to 4 deals

Inside From

$287

58% Off List

List Price

$683

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$348

48% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 11, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 11, 2026 from Miami, Florida

Up to 3 deals

Inside From

$348

48% Off List

List Price

$673

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Oceanview From

$963

59% Off List

MSC Cruises – MSC World America

Date:

Sep 12, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 12, 2026 from Miami, Florida

Up to 3 deals

Oceanview From

$963

59% Off List

List Price

$2,364

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$263

59% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Sep 13, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Sep 13, 2026 from Port Canaveral, Florida

Up to 3 deals

Inside From

$263

59% Off List

List Price

$648

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$383

72% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 13, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 13, 2026 from Galveston, Texas

Up to 4 deals

Inside From

$383

72% Off List

List Price

$1,353

View Expanded Details

Showing 1-25 of 1,574 results

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