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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Poesia itinerary map

10-night caribbean cruise

Inside From

$732

60% Off List

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Oct 22, 2026 View Other Dates →

Ports:

Miami → Bonaire → Oranjestad → Curacao → Cabo Rojo → Ocho Rios → Miami

Departs Oct 22, 2026 from Miami, Florida

Up to 4 deals

Inside From

$732

60% Off List

List Price

$1,816

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$611

55% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Feb 01, 2027 View Other Dates →

Ports:

Departs Feb 01, 2027 from La Romana, Dominican Republic

Up to 4 deals

Inside From

$611

55% Off List

List Price

$1,349

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$892

51% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Mar 22, 2027 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Oranjestad → Curacao → Bonaire → Saint George's → La Romana

Departs Mar 22, 2027 from La Romana, Dominican Republic

Up to 4 deals

Inside From

$892

51% Off List

List Price

$1,808

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$817

52% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 26, 2027 View Other Dates →

Ports:

Departs Apr 26, 2027 from La Romana, Dominican Republic

Up to 4 deals

Inside From

$817

52% Off List

List Price

$1,712

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$568

57% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 24, 2027 View Other Dates →

Ports:

Departs May 24, 2027 from La Romana, Dominican Republic

Up to 4 deals

Inside From

$568

57% Off List

List Price

$1,315

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$704

70% Off List

MSC Cruises – MSC World America

Date:

Sep 19, 2026 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 19, 2026 from Miami, Florida

Up to 3 deals

Balcony From

$704

70% Off List

List Price

$2,312

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$399

65% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Sep 20, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Cozumel → Costa Maya → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Sep 20, 2026 from Port Canaveral, Florida

Up to 4 deals

Inside From

$399

65% Off List

List Price

$1,141

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Balcony From

$479

75% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 20, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 20, 2026 from Galveston, Texas

Up to 3 deals

Balcony From

$479

75% Off List

List Price

$1,913

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Oceanview From

$251

63% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 21, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 21, 2026 from Miami, Florida

Up to 3 deals

Oceanview From

$251

63% Off List

List Price

$671

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$408

36% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 25, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 25, 2026 from Miami, Florida

Up to 3 deals

Inside From

$408

36% Off List

List Price

$633

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$616

74% Off List

MSC Cruises – MSC World America

Date:

Sep 26, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 26, 2026 from Miami, Florida

Up to 3 deals

Balcony From

$616

74% Off List

List Price

$2,407

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Oceanview From

$297

65% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Sep 27, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Sep 27, 2026 from Port Canaveral, Florida

Up to 4 deals

Oceanview From

$297

65% Off List

List Price

$840

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Balcony From

$449

76% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 27, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 27, 2026 from Galveston, Texas

Up to 4 deals

Balcony From

$449

76% Off List

List Price

$1,893

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$206

63% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 28, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Sep 28, 2026 from Miami, Florida

Up to 4 deals

Inside From

$206

63% Off List

List Price

$553

View Expanded Details

MSC Cruises MSC Seashore itinerary map

3-night caribbean cruise

Inside From

$275

59% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 01, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 01, 2026 from Port Canaveral, Florida

Up to 4 deals

Inside From

$275

59% Off List

List Price

$671

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$298

53% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 02, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 02, 2026 from Miami, Florida

Up to 4 deals

Inside From

$298

53% Off List

List Price

$633

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Balcony From

$808

63% Off List

MSC Cruises – MSC World America

Date:

Oct 03, 2026 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 03, 2026 from Miami, Florida

Up to 4 deals

Balcony From

$808

63% Off List

List Price

$2,199

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night caribbean cruise

Inside From

$400

64% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 04, 2026 View Other Dates →

Ports:

Port Canaveral → Nassau → Cozumel → Costa Maya → Ocean Cay MSC Marine Reserve Bahamas → Port Canaveral

Departs Oct 04, 2026 from Port Canaveral, Florida

Up to 4 deals

Inside From

$400

64% Off List

List Price

$1,121

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Balcony From

$450

73% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 04, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 04, 2026 from Galveston, Texas

Up to 5 deals

Balcony From

$450

73% Off List

List Price

$1,676

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$209

68% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 05, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 05, 2026 from Miami, Florida

Up to 5 deals

Inside From

$209

68% Off List

List Price

$643

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$334

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 09, 2026 View Other Dates →

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 09, 2026 from Miami, Florida

Up to 4 deals

Inside From

$334

44% Off List

List Price

$593

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$574

67% Off List

MSC Cruises – MSC World America

Date:

Oct 10, 2026 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 10, 2026 from Miami, Florida

Up to 4 deals

Inside From

$574

67% Off List

List Price

$1,744

View Expanded Details

MSC Cruises MSC Seashore itinerary map

4-night caribbean cruise

Inside From

$326

52% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 11, 2026 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Oct 11, 2026 from Port Canaveral, Florida

Up to 5 deals

Inside From

$326

52% Off List

List Price

$680

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$478

65% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 11, 2026 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 11, 2026 from Galveston, Texas

Up to 5 deals

Inside From

$478

65% Off List

List Price

$1,353

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$231

64% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Oct 12, 2026

Ports:

Miami → Nassau → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 12, 2026 from Miami, Florida

Up to 5 deals

Inside From

$231

64% Off List

List Price

$643

View Expanded Details

Showing 1-25 of 1,525 results

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