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Best South America Cruises

Showing 726-750 of 826 results
4-night south america cruise
Inside From
$479
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MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 06, 2028 from Santos, Brazil
Up to 1 deal
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3-night south america cruise
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$439
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MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 16, 2028 from Santos, Brazil
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7-night south america cruise
Inside From
$869
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 18, 2028 from Santos, Brazil
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8-night south america cruise
Inside From
$924
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MSC Cruises – MSC Splendida
4.79 Reviews
Departs Mar 27, 2028 from Rio de Janeiro, Brazil
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7-night south america cruise
Balcony From
$4,889
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Mar 04, 2028 from Barranquilla, Colombia
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18-night south america cruise
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 19, 2026 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
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33-night south america cruise
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 19, 2026 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
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16-night south america cruise
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Holland America – Oosterdam
4.2213 Reviews
Departs Nov 18, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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27-night south america cruise
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Holland America – Volendam
4.374 Reviews
Departs Nov 25, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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20-night south america cruise + tour
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 02, 2026 from Rio de Janeiro, Brazil
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21-night south america cruise + tour
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 07, 2026 from Buenos Aires, Argentina
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21-night south america cruise + tour
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 16, 2026 from Lima (Callao), Peru
Up to 1 deal
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22-night south america cruise + tour
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Jan 01, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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22-night south america cruise + tour
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Jan 18, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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22-night south america cruise
Inside From
$4,674
Holland America – Oosterdam
4.2213 Reviews
Departs Feb 01, 2027 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
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15-night south america cruise
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Holland America – Oosterdam
4.2213 Reviews
Departs Mar 09, 2027 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Aug 18, 2027 from Barranquilla, Colombia
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7-night south america cruise
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AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Oct 30, 2027 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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21-night south america cruise + tour
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Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 30, 2027 from Lima (Callao), Peru
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31-night south america cruise
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Holland America – Oosterdam
4.2213 Reviews
Departs Nov 18, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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30-night south america cruise
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Holland America – Volendam
4.374 Reviews
Departs Nov 22, 2026 from New York City, New York
Up to 2 deals including an Avoya Exclusive
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15-night south america cruise
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Holland America – Oosterdam
4.2213 Reviews
Departs Dec 04, 2026 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
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22-night south america cruise
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Holland America – Oosterdam
4.2213 Reviews
Departs Dec 19, 2026 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
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41-night south america cruise
Inside From
$10,284
Holland America – Zaandam
4.5133 Reviews
Departs Jan 03, 2027 from Fort Lauderdale, Florida
Avoya Exclusive Rate
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22-night south america cruise
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Holland America – Oosterdam
4.2213 Reviews
Departs Jan 10, 2027 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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